Based on the evaluation of 48 dyslexic subjects ages 11-50, reading 12 texts with 12 different fonts, they determined that reading performance was best with sans serif, monospaced, and roman fonts used in the study. They also found that reading was significantly impaired when italic fonts were used.
Use of the OpenDyslexic font did not enhance text readability or reading speed. The study participants strongly preferred Verdana or Helvetica over the OpenDyslexic alternative.
Good Fonts for Dyslexia – An Experimental Study


Discussion